
A new study shows enhanced CoQ10 benefits of grapefruit juice
Taking your CoQ10 supplement daily with grapefruit juice can increase your effectiveness in a surprising 50 percent, according to a new Japanese study.
A 2010 study by the University of Hokkaido suggests that intestinal absorption of coenzyme Q10 has improved considerably with the introduction of grapefruit juice. The juice increases the bioavailability of coenzyme by inhibiting the production of a cell membrane Protien called P-glycoprotein specifically, the researchers said.
CoQ10 is a naturally occurring vitamin-like substance found in every cell of body but is concentrated in the heart, liver, kidneys and pancreas. It is present in mitochondria or "power stations" each cell, where it plays a crucial role in the production of chemical energy.
The coenzyme is necessary for the basic functioning of all cells, but the body's ability to produce peaks at about twenty years of age and declines rapidly after age 40. Although supplementation is a solution low absorption and bioavailability of less than optimum are longstanding problems with CoQ10 supplements. The results of Japanese study suggests that the "co-administration CoQ10 with the juice of grapefuit constitutes an easily accessible way to improve intestinal absorption. "
But while the ability to carry the juice out the activity of protein increases the amount of CoQ10 in the cell can absorb, the same action can have serious negative effects on the body's ability to absorb certain prescription drugs. Grapefruit juice has been shown to interfere with the production of enzymes that metabolize certain drugs, including statins commonly prescribed for hypertension and medications for high cholesterol and irregular heartbeat.
People who are taking medications are advised to consult your doctor before adding grapefruit juice in your diet.
In addition to its role in energy production at the cellular level, CoQ10 has proved a potent antioxidant able to reduce, repair and even prevent damage from free radicals. The byproducts of cellular oxidation, free radicals are chemically unstable molecules cleansing and damage other cells. This damage has been associated with a number of diseases and is involved in almost all age-related disorders.
A growing body of international research indicates that supplemental CoQ10 may be effective adjuvant treatment for many diseases, including heart disease, high blood pressure, gum disease, diabetes, and both Parkinson's and Alzheimer's disease.
In addition, low levels of coenzyme are strongly associated with certain cancers, including breast, lung, prostate, pancreas, colon and kidney, raising the possibility of supplementation as a potential treatment.
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